Estrogen-mediated hemangioma-derived stem cells through estrogen receptor-α for infantile hemangioma
نویسندگان
چکیده
منابع مشابه
Estrogen-mediated hemangioma-derived stem cells through estrogen receptor-α for infantile hemangioma
BACKGROUND Infantile hemangiomas (IHs) are the most common benign vascular tumor of infancy. They occur more frequently in female infants. The cause of hemangioma is currently unknown; however, current studies suggested the importance of estrogen (E2) signaling in hemangioma proliferation. METHODS Hemangioma-derived stem cells (HemSCs) were cultured with estrogen for 48-72 h; the cell viabili...
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Infantile hemangioma is a benign endothelial tumor composed of disorganized blood vessels. It exhibits a unique life cycle of rapid postnatal growth followed by slow regression to a fibrofatty residuum. Here, we have reported the isolation of multipotential stem cells from hemangioma tissue that give rise to hemangioma-like lesions in immunodeficient mice. Cells were isolated based on expressio...
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Infantile periocular hemangiomas (IPH) are common benign vascular tumors that present early in childhood. They typically show a rapid nonlinear growth pattern a few weeks after birth during a proliferative phase, then continue with an involution phase and may result in serious ocular or systemic complications. Theses tumors may present in a range of small isolated lesions to multiple, diffuse i...
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ژورنال
عنوان ژورنال: Cancer Management and Research
سال: 2017
ISSN: 1179-1322
DOI: 10.2147/cmar.s138687